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Find cheap flights from San Francisco to South America from $157

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to South America departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Wed 7/10
Wed 7/17

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Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$520
Bogotá
Bogotá1 stop$356
Buenos Aires
Buenos Aires3 stops$917
Medellín
Medellín1 stop$369
Sao Paulo
Sao Paulo1 stop$616
Cartagena
Cartagena1 stop$379
Santiago
Santiago2 stops$519
Rio de Janeiro
Rio de Janeiro1 stop$746
Quito
Quito1 stop$451
Guayaquil
Guayaquil1 stop$456
Cali
Cali1 stop$454
Cusco
Cusco2 stops$733
Pereira
Pereira2 stops$416
Barranquilla
Barranquilla1 stop$397
Montevideo
Montevideo2 stops$781
Caracas
Caracas1 stop$2,165
Santa Marta
Santa Marta1 stop$375

Good to know

Low season

August

High season

December

Cheapest flight

$157
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 41% increase in price.
Flight from San Francisco to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Francisco to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to San Francisco with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 17% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from San Francisco to South America

Need help choosing which airline to fly with from San Francisco to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10295 reviews
7.4Food
7.9Comfort
8.0Entertainment
8.2Boarding
8.6Crew
Airline reviews

There was plenty of overhead room but half of the passengers were told they had to check their carryon bags. My partner and I checked in as early as possible and our seats were split across the aisle.

4.0 OkayBrooke, Jun 2024SFO - MSP
Read more about Delta reviews

There was plenty of overhead room but half of the passengers were told they had to check their carryon bags. My partner and I checked in as early as possible and our seats were split across the aisle.

Flew first class so everything was great. But maybe because the flights were red eye, no meals were served, just chips. I flew Alaska Air 1st class at 9PM (2 hour flight) and they served beef short rib sliders!

There was a loud squeaky sound the whole time we were flying.

I didn’t not like that I could not select my seat and ended up with the worse seat.

The landing was bad and the hostess came two times and i was sleeping but when she served the person that nexts to me I woke up and she didn’t even asked me if I need any drink or snacks two times!!!!

Plane was late because of a mechanical malfunction and the food listed as available was not. Flight attendants seem over worked and under paid. They just done seem happy. And that can be seen in their faces.

Waited 3 hours on a plane to de-ice due to manpower issues. Waited another hour and a half once we landed because of a gate issue. Missed my connections. Created. A total of 13 hours of delay.

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

Plane was turned around due to fog half way into the flight, Delta did not properly direct passengers to stay on same flight and instead failed to properly rebook on Alaska

Honestly, I didn’t expect that I will experience this long time wait during the check in. There was only one person who was taking care of the passengers for the economy class and it took us to wait about one hour to do our check i. As a result we barely get to the airplane as the gate was at the end of the airport. That is totally not professional where one crue is working at the registration desk with economy and 3-4 crues are helping for the business class.

The seats had plenty of leg room and the staff were very nice.

Copa performed as expected for the amount of money I was willing to spend for the flight; it wasn’t exceptional but it was not bad in any way either. The crew was good; friendly and straightforward. The food was airplane food, so no expectations there and the entertainment was lacking but that was my fault for owning an IPhone with a charging port that’s not compatible with the rest of the world. I’d fly Copa again.

Left my bags in origin city on a business class ticket , spent about 2-3 days in the same clothes plus the flight .

the planes are not modern there are no phone chargers

As usual, the flight with normal legroom was not very comfortable, but the second flight was much better because we had paid for extra legroom. It was very nice to check our bags without an extra fee.

LOCKED MY BAG WITHOUT CONSENT. Had to have my zippers cut upon arrival in Costa Rica.

Pros: "The seats in economy were confortable. The best thing was Copa gave us seats in the second line and my family traveled together."
Cons: "Coffe service could better the experience"
Pros: "The crew was very interested on help and attentive with the passengers. But the seat wasn't comfortable. The design of the cushion is not the best to be seating"
Pros: "You were on time, that is the most important thing in a fly"
Cons: "You could improve your entertainment, you are not a cheap company"
Pros: "That there was seltzer"
Cons: "The management of preparing the flight and plane so that it was ready for the trip!!"

They offered food. The crew passed by again offering water. I enjoyed the two seating section. I think is very comfortable instead of the three seat way, unless you seat in the middle; which it's not bad, but I wouldn't prefer. All and all, I think the lay out of the seating rows are better than other airlines so far( I haven't tried many anyways). The lay out makes the getting in and out to use the restroom less uncomfortable and cramped. First time flying with Latam. I will fly with them again

Everything was as you would expect in coach - fine. Flight was close to on time.

I missed my plane because there was a lot of people during the migration process. The airline has the chance to care for their clients and they could get the passengers missing in the flight. I lost a day of work and Montfort transportation to go back home and go to the airport again. Unfortunately the airline doesn’t care about that. I use latam at least 4 times a year, so I guess I need to be treat better. In addition, one on my baggages didyarricw to my destination. So frustrated with this trip.

No air in the middle rows. Had a hard time breathing. Was dying of heat.

Not very good, they nickel & dime you for better seats & pay extra for the checking in bag, bad service all the way around

Horrific checkin procedure with neither Delta nor Latam figuring out how to check me in. 4 hrs on customer support with both and both airlines pointing to each other who should do checking. I was not checked in until morning of flight, which for international flight is concerning.

It was a good experience, the flight was a little too long & the food was ok

Awful, horrible customer service. Flight got delayed and had to spend y the night in Bogota as a result. Very poor

Liked check in process To improve: food and beverages. Not second round was offered and meal had no salad.

the flight from Boston to Curitiba was on time actually 30 minutes earlier. latam was not able to unload the luggage for custom checkup in Sao Paulo ii took two and half hours . i missed the flight to Curitiba spend the night in hotel and then flying in the morning to Curitiba

Why does it have to be painful to fly long distances?

Horrible, the flights kept delaying, so it is obvious that we won't be able to make it to the next connection. No easier/real agent on site to help you figure this out. UA agent on other counters refuse to assist you and direct us to use the QR code/call customer service. So inefficient and poor. While technology seems convenient, but it's not the best interest/experience for customers need help while there is active issue need assistance.

Food is very bad and entertint not too many options ... flight attendet service is not good

Flight was delayed due to the late arrival of the catering truck, which is quite unacceptable. There was a beverage service, but no pretzel, or cookie, or nuts were served in coach.

Aisle chair was good and liked the foot bar preventing you from putting your foot in the isle, The breakfast on this international flight to Zurich was horrible (Europeans, specially, used to good food) may make this a dealbreaker for booking with United Airlines again. I agreed with my Spanish fellow passenger.

On time take off…US cabins look tired and need of refresh!

Backpack should NOT allowed put in the flight bin , only put it under the seat. I can't find space put my carry on luggage!!! and I pay for it ! that was very bad experience

Hated every minute of it. This flight should have only taken 1.5hrs but was delayed over 10hours. Now I am being told I cannot be compensated or refunded my ticket price or extra leg room, which I purchased but did not receive, because the airline is throwing the blame on the 3rd party I purchased tickets through and 3rd party putting the blame on airline. No one wants to help. They received their money and that's all they care about. Im going on 3 days of still trying to get to my final destination, had to cancel car rental, car insurance and hotel. Currently staying in airport until hotels open up. Thank you Lufthansa, Kayak, Underpricer and United for making this trip the worst ever.

Crew was great and did their best to make us comfortable and captain came out at the beginning to announce why the flight was delayed, weather situation up ahead, and kept us updated throughout the flight.

United WiFi is consistently unusable (it can take 10 mins to load a single web page). If you need Wifi to do work, be prepared to lose half a day of productivity.

The flight was delayed several times without explanation. The seats were terribly uncomfortable and wifi isn’t included. All these make for a less than ideal flight.

Internet service was erratic. Crew service was poor and slow. My luggage on this non-stop flight was lost and not recovered

Flight was 1/2 hour delayed leaving Phoenix. Otherwise it was an average flight. Flight crew on this trip was very nice.

Horrible - they lied to me about baggage & boarding, even though I specifically spoke to their agents the day before my flight about my issue. When I showed up they did not let me board and stranded me at my airport until I bought a new flight with money I did not have to spend.

Not sure why JAL partnered with American Airlines because their service is no where near similar. Flight attendants were not friendly and didn’t smile. Food was horrible…

The experience was great and much better than the flight going out. of course I was in first class but the service was excellent

Comfort of seats, ease of boarding. Food selection could be better

Food options were limited which is absolutely embarrassing for a Flight of this size The staff did not come around as much and I am not accustomed to such poor service from American Airlines Drinks I believe were limited to soda and water

Crew were attentive and friendly. Flight was smooth and early! I enjoyed the less crowded plane. Thank you!

We are gluten free, there were not any available complimentary gluten free options.

Book cheap flights from San Francisco to South America

Recent round-trip flight deals

9/3Tue
1 stopAvianca
9h 45mSFO-BOG
9/17Tue
1 stopAvianca
10h 00mBOG-SFO
$356
8/31Sat
1 stopUnited Airlines
19h 05mSFO-BOG
9/17Tue
1 stopUnited Airlines
18h 24mBOG-SFO
$367
9/3Tue
1 stopAmerican Airlines
20h 34mSFO-BOG
9/10Tue
2 stopsAmerican Airlines
17h 28mBOG-SFO
$372
8/12Mon
1 stopAmerican Airlines
19h 31mSFO-BOG
8/19Mon
1 stopAmerican Airlines
23h 56mBOG-SFO
$378
11/3Sun
1 stopCopa Airlines
10h 32mSFO-CTG
11/13Wed
1 stopCopa Airlines
16h 51mCTG-SFO
$379
10/19Sat
1 stopLATAM Airlines
13h 50mSFO-BOG
11/9Sat
1 stopLATAM Airlines
15h 03mBOG-SFO
$389
11/5Tue
2 stopsLATAM Airlines
25h 37mSFO-BOG
11/12Tue
2 stopsLATAM Airlines
16h 58mBOG-SFO
$393
9/2Mon
2 stopsDelta
20h 48mSFO-BOG
9/8Sun
2 stopsDelta
19h 01mBOG-SFO
$394
8/31Sat
2 stopsDelta
20h 56mSFO-BOG
9/16Mon
1 stopDelta
21h 33mBOG-SFO
$412
11/2Sat
1 stopCopa Airlines
19h 27mSFO-CTG
11/13Wed
1 stopCopa Airlines
19h 37mCTG-SFO
$421

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Recent one-way flight deals

8/11Sun
1 stopUnited Airlines
19h 41mSFO-BOG
$157
8/21Wed
1 stopAvianca
9h 45mSFO-BOG
$158
8/23Fri
1 stopAmerican Airlines
19h 31mSFO-BOG
$162
9/1Sun
2 stopsAmerican Airlines
16h 24mSFO-BOG
$164
6/18Tue
1 stopDelta
20h 11mSFO-BOG
$172
12/4Wed
2 stopsLATAM Airlines
18h 37mSFO-BOG
$178
8/26Mon
2 stopsDelta
17h 26mSFO-BOG
$190
12/4Wed
1 stopLATAM Airlines
17h 00mSFO-BOG
$191
8/14Wed
1 stopCopa Airlines
10h 22mSFO-MDE
$202
7/30Tue
1 stopCopa Airlines
19h 40mSFO-UIO
$202

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Last minute flights from San Francisco to South America

Last minute flight, train and bus deals

6/11Tue
multi-stopUnited Airlines
21h 44mSFO-BOG
6/18Tue
multi-stopUnited Airlines
25h 39mBOG-SFO
$446
6/12Wed
multi-stopUnited Airlines
25h 54mSFO-CTG
6/17Mon
multi-stopUnited Airlines
16h 15mCTG-SFO
$487
6/12Wed
multi-stopAmerican Airlines
15h 55mSFO-MDE
6/20Thu
multi-stopAmerican Airlines
17h 13mMDE-SFO
$524
6/11Tue
multi-stopDelta
20h 11mSFO-BOG
6/20Thu
multi-stopDelta
12h 02mBOG-SFO
$556
6/11Tue
multi-stopDelta
20h 11mSFO-BOG
6/21Fri
multi-stopDelta
20h 32mBOG-SFO
$561
6/11Tue
multi-stopCopa Airlines
11h 30mSFO-BOG
6/16Sun
multi-stopCopa Airlines
19h 55mBOG-SFO
$577
6/15Sat
multi-stopAmerican Airlines
25h 46mSFO-BOG
6/20Thu
multi-stopAmerican Airlines
24h 08mBOG-SFO
$583
6/11Tue
multi-stopCopa Airlines
10h 24mSFO-CTG
6/16Sun
multi-stopCopa Airlines
16h 06mCTG-SFO
$606
6/12Wed
multi-stopLATAM Airlines
21h 52mSFO-BOG
6/20Thu
multi-stopLATAM Airlines
12h 02mBOG-SFO
$633
6/12Wed
multi-stopLATAM Airlines
21h 52mSFO-BOG
6/18Tue
multi-stopLATAM Airlines
15h 59mBOG-SFO
$638

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